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Fig. 5 | BMC Veterinary Research

Fig. 5

From: Genetic characterization and pathogenicity of two recombinant PRRSV-2 strains from lineages 1, 3, 5, and 8 emerged in China

Fig. 5

Gross pathology, microscopic lung lesions and lung IHE examination of the inoculated piglets. (A) Severe interstitial pneumonia with consolidation was observed in FJLIUY-2017-challenged piglets. (B) Moderate interstitial pneumonia with consolidation were observed in PRRSV2/CN/G8/2018-challenged piglets. (C) No obvious gross lung lesions were observed in control group. Microscopic lesions in the lungs of piglets inoculated with strains FJLIUY-2017 (D) and PRRSV2/CN/G8/2018 (E) showed significant lung lesions characterized by interstitial pneumonia compared to piglets inoculated with DMEM (F). Lung IHE examination in the inoculated piglets, PRRSV-positive signals in bronchial epithelial cells and macrophages of lung could be detected from piglets challenged with PRRSV strains FJLIUY-2017 (G) and PRRSV2/CN/G8/2018 (H), whereas no positive staining cells were detected in the control group (I)

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