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Table 2 Biochemistry characteristics during salt intervention period between the control and experimental group

From: The impact of dietary salt on the development of hypertension and gut microbiome dysbiosis in captive-bred vervet monkeys (Chlorocebus aethiops)

Parameters

Groups

T0$

T6$

T12$

Global P-Value*

Weight (Kg)

Control

5.23 ± 1.53

5.24 ± 1.47

5.40 ± 1.47

0.50

Experimental

4.72 ± 1.32

4.67 ± 1.46

4.73 ± 1.37

P-value**

0.48

0.44

0.36

Estimates (SE = 0.72)

-0.52

-0.57

-0.67

Systolic BP (mmHg)

Control

134.7 ± 26.8

130.5 ± 15.2

120.4 ± 38.8

0.09

Experimental

125.5 ± 41.9

157.8 ± 37.2

171.3 ± 35.4

P-value**

0.57

0.16

0.0034

Estimates (SE = 16.1)

-9.21

23.53

50.89

Diastolic BP (mmHg)

Control

62.9 ± 25.2

70.0 ± 17.3

68.8 ± 35.6

0.69

Experimental

56.2 ± 29.1

76.1 ± 34.6

81.3 ± 26.6

P-value**

0.65

1.00

0.28

Estimates (SE = 14.8)

-6.75

0.07

16.72

Sodium (mmol/L)

Control

149.88 ± 2.42

130.50 ± 52.75

149.88 ± 2.42

0.34

Experimental

150.13 ± 2.42

151.00 ± 1.51

151.25 ± 1.49

P-value**

0.81

0.07

0.20

Estimates (SE = 1.0)

0.25

2.04

1.38

Potassium (mmol/L)

Control

3.55 ± 0.59

3.71 ± 0.69

3.35 ± 0.21

0.05

Experimental

3.55 ± 0.46

3.40 ± 0.33

3.56 ± 0.53

P-value**

1.00

0.20

0.38

Estimates (SE = 0.24)

0.00

-0.32

0.21

Chloride (mmol/L)

Control

110.38 ± 2.67

108.43 ± 1.99

107.75 ± 2.55

0.004

Experimental

108.75 ± 2.25

108.25 ± 1.83

110.38 ± 1.92

P-value**

0.21

1.00

0.05

Estimates (SE = 1.26)

-1.63

0.00

2.63

Bicarbonate (mmol/L)

Control

28.63 ± 4.52

29.51 ± 2.60

33.11 ± 2.35

0.91

Experimental

27.85 ± 6.76

28.59 ± 6.03

31.41 ± 3.01

P-value**

0.73

0.64

0.45

Estimates (SE = 2.20)

-0.78

-1.04

-1.70

Urea (mmol/L)

Control

6.20 ± 1.42

6.46 ± 1.64

5.11 ± 1.83

0.39

Experimental

6.63 ± 0.98

7.29 ± 1.39

5.64 ± 0.82

P-value**

0.55

0.14

0.46

Estimates (SE = 0.70)

0.43

1.08

0.53

Creatinine (mmol/L)

Control

53.88 ± 12.90

61.71 ± 14.80

59.25 ± 10.93

0.98

Experimental

54.00 ± 12.40

63.50 ± 13.47

62.13 ± 9.51

P-value**

0.98

0.80

0.63

Estimates (SE = 5.90)

0.13

1.51

2.88

Anion GAP (mmol/L)

Control

9.29 ± 2.69

11.43 ± 2.88

9.13 ± 1.64

0.42

Experimental

10.29 ± 1.60

11.57 ± 2.07

9.63 ± 2.26

P-value**

0.53

0.80

0.66

Estimates (SE = 1.20)

0.76

0.30

0.50

Calcium (mmol/L)

Control

2.16 ± 0.07

2.17 ± 0.08

2.26 ± 0.05

0.20

Experimental

2.24 ± 0.09

2.25 ± 0.08

2.26 ± 0.06

P-value**

0.08

0.10

1.00

Estimates (SE = 0.04)

0.08

0.08

0.00

Magnesium (mmol/L)

Control

0.62 ± 0.05

0.65 ± 0.07

0.64 ± 0.05

0.36

Experimental

0.60 ± 0.06

0.64 ± 0.05

0.63 ± 0.06

P-value**

0.63

0.89

0.78

Estimates (SE = 0.03)

-0.02

0.00

-0.01

AST (IU/L)

Control

61.75 ± 14.89

67.71 ± 18.41

57.00 ± 19.39

0.20

Experimental

64.25 ± 14.49

57.88 ± 16.80

53.38 ± 14.16

P-value**

0.83

0.24

0.75

Estimates (SE = 11.22)

2.50

-14.29

-3.63

ALP (IU/L)

Control

117.13 ± 38.77

128.57 ± 47.67

112.38 ± 38.91

0.39

Experimental

158.00 ± 52.15

174.25 ± 45.68

148.25 ± 35.98

P-value**

0.08

0.04

0.12

Estimates (SE = 21.59)

40.88

49.62

35.88

GGT (IU/L)

Control

49.38 ± 17.94

49.29 ± 22.90

51.00 ± 20.96

0.90

Experimental

55.25 ± 19.83

58.00 ± 13.33

57.50 ± 17.25

P-value**

0.55

0.61

0.51

Estimates (SE = 9.73)

5.88

5.02

6.50

ALT (IU/L)

Control

45.63 ± 17.41

43.29 ± 16.71

43.50 ± 19.45

0.62

Experimental

47.13 ± 24.41

59.50 ± 25.17

44.63 ± 15.92

P-value**

0.90

0.33

0.92

Estimates (SE = 11.67)

1.50

11.64

1.13

  1. $ Descriptive mean ± standard deviation; n = 16 (8 control and 8 experimental)
  2. ** P-value for differences at individual time points
  3.  • Global P values for T0 to T12; P < 0.05 is considered significant
  4.  • Alanine Aminotransferase (ALT); alkaline phosphatase (ALP); aspartate Aminotransferase (AST); gamma-glutamyl transpeptidase (GGT)
  5.  • Estimates average difference experimental-control group
  6. SE standard error of estimate